Serie A Matchday 16 betting preview, free picks & best odds

Matchday 16 of Serie A 2024-25 features a full slate of 10 games between Friday and Monday, including a thrilling clash between Lazio and defending champions Inter Milan. Here are our free soccer betting picks for this week’s Serie A matchups.

Empoli v Torino

Friday, December 13 – 8:45pm CET – Stadio Carlo Castellani

Empoli, sitting 10th, ended their three-match winless run with a 4-1 victory over Verona last time out, while Torino remain 12th after six league games without a win. Expect the hosts to grind out a third successive win in all competitions.

Cagliari v Atalanta

Saturday, December 14 – 3pm CET – Sardegna Arena

Serie A leaders Atalanta will be eager to bounce back for their Champions League loss to Real Madrid when they face 15th-placed Cagliari, who lost their last outing against Fiorentina. Ademola Lookman scored his 11th goal of the season in midweek, and online bookmakers are paying +150 for the Atalanta forward to add to his tally.

Udinese v Napoli

Saturday, December 14 – 6pm CET – Stadio Friuli

Down to second on the Serie A table following Sunday’s 1-0 loss to Lazio, Napoli will be looking to return to winning ways on their trip to Udinese, who are ninth. Unbeaten in their last nine meetings, with seven wins and two draws, expect the Azzurri to continue dominating this fixture.

Juventus v Venezia

Saturday, December 14 – 8:45pm CET – Juventus Stadium

After their commanding 2-0 win over Manchester City in the Champions League, sixth-placed Juventus will be keen to end their three-game run of draws when they face bottom-placed Venezia. Dusan Vlahovic was on target in midweek, and top sports betting sites are paying +240 for the Juve forward to open the scoring in Turin.

Lecce v AC Monza

Sunday, December 15 – 12:30pm CET – Stadio Via del Mare

Lecce, in 16th, were hammered 4-1 by Roma last time out, while Monza are second from bottom after losing 2-1 to Udinese. Unbeaten in their last four meetings, the hosts look poised to claim maximum points against the Biancorossi, who have managed just one win all season.

Bologna v Fiorentina

Sunday, December 15 – 3pm CET – Stadio Renato Dall’Ara

After being held to a goalless draw by Benfica in the UCL, eighth-placed Bologna face an uphill battle against fourth-placed Fiorentina, who are strong contenders for the Scudetto. Clinical in front of goal, the Viola could very well secure their eighth consecutive league win against their inconsistent hosts.

Parma v Hellas Verona

Sunday, December 15 – 3pm CET – Stadio Ennio Tardini

Parma slipped to 13th following their 3-1 hammering by Inter Milan last Friday, while Verona dropped to the bottom three after suffering their fourth straight league defeat. Parma have shown they can rise to the occasion when it matters, so trust them to secure a crucial win against Serie A’s worst defence.

Como v AS Roma

Sunday, December 15 – 6pm CET – Giuseppe Sinigaglia Stadium

Roma, sitting 11th, ended their four-game losing streak with a much-needed win over Lecce, while 17th-placed Como have not won since September. Gradually improving under manager Claudio Ranieri, the Giallorossi should do just enough to win on the road.

AC Milan v Genoa

Sunday, December 15 – 8:45pm CET – Giuseppe Meazza Stadium

Milan, in seventh, will be aiming to ascend higher up the table when they take on Genoa, who remain in 14th following their goalless draw with Torino. Rafael Leao got on the scoresheet during Milan’s Champions League win over Crvena Zvezda, and top bookie Bovada is offering decent odds of +187 for the Portuguese winger to strike again.

Lazio v Inter Milan

Monday, December 16 – 8:45pm CET – Stadio Olimpico

After losing 1-0 at Bayer Leverkusen in the Champions League, third-placed Inter Milan have a tough assignment against fifth-placed Lazio, who beat Napoli in their last outing. Both boasting impressive attacking strengths, this encounter could end all square for the second consecutive time.

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