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Bills vs Patriots NFL Betting Preview & Picks

Buffalo Bills @ New England Patriots

Latest NFL Betting Ods & Match Info

NFL Betting odds Moneyline: Bills -345 at Bovada | Bears +285 at Bovada
Line: Bills -7 | O/U: 47
When Monday, December 28 – 20:15pm Local time
Where Gillette Stadium, Foxborough, United States
Watch Live CBS (US), Sky Sports (UK), Foxtel, Kayo (AU), NFL Gamepass

Buffalo Bills vs New England Patriots Betting Preview

The Buffalo Bills take on the New England Patriots and look to sweep the second of two meetings for a chance at a #2 seed in the AFC.

The Buffalo Bills are nearing full playoff mode in the second to last week of the NFL regular season and do not expect the New England Patriots to stop them. Having won the last four games and the last seven out of eight games proves this for the Bills. So what NFL betting odds should you be taking a look at for this Monday Night Football Showdown?

The Bills are 9-5 Against the Spread (ATS) overall and 4-3 ATS on the road. They are improving with every victory as they have also outscored their last four opponents by at least ten points or better. On the comeback, the Patriots have lost their last two games and are 6-8 ATS coming into this contest. These are all indications that Buffalo should cover the spread. It is important to note that while at home in Foxboro, the Pats are 4-2 ATS and they covered in their last matchup against the Bills, losing 21-24 (+4 Underdog). All in all, this is still the Bill’s game to lose and I think they have a Super Bowl on their mind and will take care of business on the road. Lay the seven points.

Under 47 Points (-110)This is more intuition than statistics. The Patriots have a slow pace of play and will look to limit the number of times Josh Allen can touch the ball (similar to a Patrick Mahomes matchup). Combine this with a second divisional matchup and I think that it will be a lower scoring game than fans hope for, unless you’re betting the under of course.

Beasely has been thriving in both targets and yardage throughout the games where John Brownhas been absent. Guess what? Brown was activated from Injured Reserve but was subsequently placed on the reserve/COVID-19 list and will be unavailable tonight. In Beasley’s last four games without Brown active, he has averaged 77 receiving yards per game, bringing inover 100 yards in two of those games. Furthermore, the Patriots Defense strives to take awaythe WR1 against most teams they play. If this is the case with Diggs, Beasley could see his fair share of work. This is much to my chagrin, as I am playing against him in my fantasy matchup this week.

Despite my claim to Stefon Diggs being defended heavily by the Pats, he still is very good. Diggs has 11 Red Zone targets on the season and has a 74% Red Zone Catch Rate ( If Allen can get him the ball here, I think he will have success and find the endzone and help you cash a nice slip. Consider parlaying the two above props for a fun watch.

Buffalo Bills vs New England Patriots Betting Predictions

Buffalo Bills -7


Under 47 Points


Stefon Diggs To Score A TouchDown


Cole Beasely 65+ Receiving Yards

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