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Green Bay Packers vs San Francisco 49ers betting odds and tips

Packers @ 49ers NFL betting picks

Kickoff at 5:20pm PT (8:20pm ET)

Green Bay Packers
Moneyline odds: +135
Betting line: +3 at -111.11
Record (ATS): 8-2 (7-3)

San Francisco 49ers
Moneyline odds: -155
Betting line: -3 at -111.11
Record (ATS): 9-1 (5-4)

The Green Bay Packers are coming off a bye week and head to the left coast to take on the San Francisco 49ers in a huge Sunday night primetime game in NFL Week 12.

The Packers are at 8-2 and tied with the Seattle Seahawks for the second spot in the NFC behind the 49ers at 9-1. Green Bay have won five of their last six games and while in first place in the NFC North they only lead the Minnesota Vikings by one game.


The 49ers are coming off a 36-26 win over the Arizona Cardinals that was much closer than the score indicated. They scored a late TD to take the lead and then returned a fumble for a score at the very end. The result ensured San Francisco stayed one game up on the Seahawks in the NFC West.

These teams met last season in Green Bay where the Packers beat the 49ers 33-30. While the Packers did not cover in last season’s matchup, they are 11-5-2 ATS in their last 18 games against San Fran.




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The Packers are coming off a 24-16 win over the Carolina Panthers where they stopped Christian McCaffrey at the goal-line as time expired to preserve the win. Green Bay had fewer overall yards (401-388) but forced two turnovers and did not commit any. They also rushed for 163 yards.

Aaron Rodgers passed for 233 yards with no touchdowns and no interceptions in the win over the Panthers, which was at Lambeau Field in snowy conditions. He has eight touchdowns in his last four games and has not been picked off in that run.

The Packers had a great ground attack in the last game with Aaron Jones rushing for 93 yards and three touchdowns and Jamaal Williams rushing for 48 yards.

In their last game the 49ers outscored the Cardinals 19-7 in the fourth quarter and narrowly won even though they outgained Arizona 442 yards to 266. Jimmy Garoppolo had a big game, passing for 424 yards with four touchdowns and two interceptions.

Garoppolo needed to play well, as he got no help from the run game. Although SF rank second in the league in rushing yards per game, they managed only 34 in the win over Arizona. Tevin Coleman led the team with 14 rushing yards in the absence of leading rusher Matt Breida, who missed the last game and is doubtful for Green Bay.

Compared to the early rounds of the season, the Packers’ defense has not looked nearly as good in the last few games. They rank 23rd in the NFL in pass defense and 25th in run defense, while the 49ers have the NFL’s top-ranked pass defense and sit 20th in run defense.

Green Bay Packers betting trends

  • Packers are 4-1 ATS in their last five road games
  • Packers are 5-0 ATS in their last five games facing teams with a winning record
  • Packers are 7-3 ATS in their last 10 games
  • Packers have an Over record of 20-8 in their last 28 road games

San Francisco 49ers betting trends

  • 49ers are 1-3-1 ATS in their last five games
  • 49ers are 9-20-1 ATS in their last 30 games facing teams with a winning record
  • 49ers have an Over record of 4-0 in their last four games

Packers vs 49ers head-to-head trends

  • Packers are 11-5-2 ATS in their last 18 games against the 49ers
  • Packers are 6-2-1 ATS in their last nine road games against the 49ers
  • In the last nine games between these teams the Over record is 7-2

Packers @ 49ers NFL betting predictions

Green Bay Packers to win – +135 at Bovada

While the 49ers are a solid team, they are not the cream of the crop like the Packers are. The cream will rise to the top in this NFC matchup, as Rodgers will have a solid game with help from the ground. Green Bay will definitely cover the spread, but they should be good enough to clinch the win as well.


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