NCAA Tournament Second Round Picks & Parlay – March 23

The second round of March Madness 2025 is underway, and Sunday’s slate is stacked with high-stakes matchups as teams fight for a place in the Sweet 16.

Saturday delivered fireworks—including a near-upset scare for Tennessee—and Sunday is shaping up to bring even more bracket drama, with heavyweights like Arizona, Duke, and Illinois in action.

With several contests looking tight on paper, bettors have plenty of angles to work with.

Let’s check out the best bets for Sunday’s NCAA Tournament showdown.

Second Round betting picks – March 23

Duke v Baylor

This heavyweight clash features two elite programmes with deep tournament pedigrees. Baylor has been a bit erratic defensively this season, while Duke’s young core is starting to click at just the right time.

Oregon v Arizona

Arizona looked sharp in their first-round blowout and comes into this all-Pac-12 battle brimming with confidence. Oregon’s size could present a challenge early, but the Wildcats are far more efficient on both ends and have the firepower to pull away late. Arizona has covered the spread in six of their last seven against Pac-12 opponents.

Arkansas State v North Texas

North Texas thrive in slow, grind-it-out games, ranking among the lowest tempo teams in the field. Arkansas State play a faster style, but they could struggle to get good looks against one of the best defensive units in the country. With the Mean Green dictating pace, this shapes up as a low-scoring affair.

March Madness Parlay of the Day

March Madness rolls into Day 5, and the excitement is already in full swing. As the tournament continues, bettors can jump into the action with top betting sites offering odds on every game from the opening tip to the final buzzer.

Duke -11.5

Arizona -3.5

Arkansas State v North Texas under 136.5

TOTAL RETURN: $6.71

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