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Seattle Seahawks vs San Francisco 49ers betting odds and tips

Seahawks @ 49ers NFL betting tips

5:15pm PT Monday, November 11 at Levi’s Stadium – Santa Clara, CA

Seattle Seahawks
Moneyline odds: +230 at Bovada
Betting line: +6 at -111.11
Record (ATS): 7-2 (4-5)

San Francisco 49ers
Moneyline odds: -270 at Bovada
Betting line: -6 at -111.11
Record (ATS): 8-0 (5-3)

Welcome to our NFL predictions article for Monday night football! The Seattle Seahawks head south to face the undefeated San Francisco 49ers in a Monday night NFC West showdown.

This is a big game, especially for the Seahawks, as a loss in Santa Clara this week will make it difficult to win the NFC West title. Seattle have won two in a row, but only one of their seven wins this season has come against a team that currently has a winning record.


The 49ers are the lone unbeaten team in the NFL and boast the league’s top-ranked defense. They also rank second in the league for rushing yards with an average of 171.1 per game. The offense is working too, as San Fran have put up a total of 79 points over their past two games.

The Seahawks got a scare in their last game, beating a two-win Tampa Bay Buccaneers team 40-34 in OT. Seattle racked up 492 yards in the game and had balance but allowed the Bucs to gain 418 yards, including 319 passing yards.




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Russell Wilson bolstered his MVP resume in the win over Tampa, passing for 378 yards with five touchdowns and no interceptions. He sits top of the QB power rankings with 22 touchdowns and only one pick after nine games. Wilson faces his biggest test yet this week, as the 49ers have the top-ranked pass defense in the NFL.

Chris Carson rushed for 105 yards in the Tampa game facing the league’s no.1 run defense. He ranks fifth in the NFL in rushing yards.

In the 49ers’ last game, they beat the Arizona Cardinals 28-25 behind another impressive performance from Jimmy Garoppolo, who passed for a season-high 317 yards with four touchdowns and no interceptions. His last two games have returned six passing scores and only one pick.

In the Arizona win Matt Breida rushed for 78 yards at 5.2 yards per carry. Emmanuel Sanders had 117 receiving yards and a touchdown in his second game with the 49ers, while star TE George Kittle had 79 receiving yards and a score.

It is hard to believe the Seahawks only rank 28th in the league in pass defense, which hurt them in their last game. Seattle’s run defense ranks 13th and will be crucial against the likes of Breida, Tevin Coleman and Raheem Mostert.

Seattle Seahawks betting trends

  • Seahawks are 8-2 ATS in their last 10 road games
  • Seahawks are 9-4-1 ATS in their last 14 Monday night games
  • Seattle has an Over record of 6-2 in their last eight road games

San Francisco 49ers betting trends

  • 49ers are 9-19-1 ATS in their last 29 games facing a team with a winning record
  • 49ers are 27-7 ATS in their last 34 Monday night games
  • 49ers have an Over record of 8-3 in their last 11 games facing a team with a winning record

Seahawks vs 49ers head-to-head trends

  • Seahawks are 11-3-1 ATS in their last 15 games facing the 49ers
  • Seahawks are 5-2 ATS in their last seven games facing the 49ers in San Francisco
  • Home team is 5-2 ATS in the last seven games between these teams
  • In the last seven games between these teams the Over record is 5-2
  • In the last seven games between these teams in San Francisco the Under record is 5-2

Seahawks @ 49ers NFL betting predictions

San Francisco 49ers -6 at -111.11 with Bovada

Are the Seahawks as good as their 7-2 record indicates? Good question. The 49ers are for real, and they will ride their defense and a strong ground game to win this Monday night matchup and cover the spread.


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