Serie A Matchday 22 betting guide & preview | January 24-27, 2025

Another exciting weekend of Serie A action is on the horizon as Matchday 22 unfolds. League leaders Napoli host Juventus, while Lazio faces Fiorentina in Rome.

Here are our free soccer betting picks for this weekend’s Serie A matchups.

Torino v Cagliari

Friday, January 24 – 8:45pm CET – Stadio Olimpico Grande Torino
Cagliari, in 14th, have shown resilience with two wins and a draw in their last three matches, while Torino, sitting 11th, are winless in five.

Given Cagliari’s unbeaten streak in their last five trips to Turin, they could maintain this trend with the top sportsbooks offering +265.

Como v Atalanta

Saturday, January 25 – 3pm CET – Giuseppe Sinigaglia Stadium
Third-placed Atalanta, winless in four matches, will look to get back on track against 13th-placed Como.

Ademola Lookman, who starred in Atalanta’s recent Champions League win, is a great pick to score again.

Napoli v Juventus

Saturday, January 25 – 6pm CET – Diego Armando Maradona Stadium
Napoli, on a six-game winning streak, will look to maintain their dominance as they host fifth-placed Juventus, who have drawn seven of their last nine matches.

Back the league leaders to hand Juve another defeat in Naples with Nags.bet.

Empoli v Bologna

Saturday, January 25 – 8:45pm CET – Stadio Carlo Castellani
Bologna, fresh from a Champions League win, will aim to capitalize on their momentum against 15th-placed Empoli, who haven’t won in six games.

Expect Bologna to claim victory against their struggling hosts.

AC Milan v Parma

Sunday, January 26 – 12:30pm CET – Giuseppe Meazza Stadium
Eighth-placed Milan will look to climb up the table as they face bottom-half Parma.

Tijjani Reijnders, with nine goals this season, is a strong contender to score again in this matchup with the top online casinos offering +160.

Udinese v AS Roma

Sunday, January 26 – 3pm CET – Stadio Friuli
Ninth-placed Roma will look to extend their dominance over 10th-placed Udinese, having won their last four encounters.

Expect the Giallorossi to come out on top again.

Lecce v Inter Milan

Sunday, January 26 – 6pm CET – Stadio Ettore Giardiniero – Via del Mare
Inter, sitting second, will aim to keep the pressure on Napoli as they face relegation-threatened Lecce.

Lautaro Martinez is in hot form and is likely to find the back of the net once again.

Lazio v ACF Fiorentina

Sunday, January 26 – 8:45pm CET – Stadio Olimpico
Fourth-placed Lazio are unbeaten in their last six home games and will aim to dispatch Fiorentina, who haven’t won in six matches.

Back Lazio to secure a straightforward win.

Venezia v Hellas Verona

Monday, January 27 – 6:30pm CET – Stadio Pier Luigi Penzo
Hellas Verona, in 17th, will seek to replicate their double over 19th-placed Venezia from their last meetings.

Back the visitors to claim another victory at +242 with Nags.bet.

Genoa v AC Monza

Monday, January 27 – 8:45pm CET – Luigi Ferraris Stadium
Genoa, in 12th, will look to secure an easy win against bottom-placed Monza, who have lost six of their last seven matches.

Expect Genoa to prevail comfortably.

Sports betting picks