49ers @ Cardinals NFL best bet & odds – Monday Night Football
- By: Sam Shulman
- November 20, 2022
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Week 11’s Monday Night Football feature is slated to be a fun divisional battle between the 4-6 Arizona Cardinals and the 5-4 San Francisco 49ers. While these two teams have grown accustomed to each other through the years, this game will be played in Mexico City and that could add some unpredictability into the mix. This is a chance for both teams to stake their playoff claim, and we have some free NFL betting picks to spice things up.
49ers @ Cardinals spread pick: San Francisco -8
Arizona are technically the home team for this game, but due to the game being in Mexico City, there is no real home-field advantage. Because of that, it is hard to bet against what is a far superior 49ers outfit. While San Francisco’s offense can be stagnant at certain times, Arizona have an awful defense and the Niners have enough playmakers to take advantage of that. Also, the San Francisco defense is a top-10 unit in the NFL and should have an easy time with an offense led by a hobbled Kyler Murray.
San Francisco 49ers -8
Arizona Cardinals TD scorer pick: James Conner
James Conner had two touchdowns last week and is firmly back as the starting running back for the Cardinals. After dealing with injuries at the start of the season, Conner had a tough time staying on the field, but last week he looked great. He is in line to receive a ton of work, and while the Niners defense is a good unit, this is a great value bet on a guy who could touch the ball 30 times.
James Conner anytime touchdown
San Francisco 49ers TD scorer pick: George Kittle
George Kittle is the uber-talented tight end for the Niners and he is in a tremendous spot to have a great game. The Cardinals cannot defend that position at all and have been exploited by tight ends all season long. As such, Kittle is going to have plenty chances to score in this matchup. Take him to score a touchdown at +165 with Bovada in a game the Niners should win with ease.
George Kittle anytime touchdown
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