Champions League betting picks | Round of 16 first-leg preview

Real Madrid will look to settle their score with Atletico when they clash in the last 16 of the Champions League, while Bayern Munich will face Bayer Leverkusen in another domestic blockbuster. Below are our free soccer betting picks for the first leg in the 2024-25 UEFA Champions League round of 16.

Club Brugge v Aston Villa

Tuesday, March 4 – 6:45pm CET – Jan Breydel Stadium

Aston Villa secured direct qualification into the last 16, while Club Brugge booked their place after edging out Atalanta in the playoff round. The inconsistent Premier League side could struggled on the road against a well-drilled counterattacking team that outclassed them on Matchday 4.

Club Brugge to win
+196 @ Nags.bet

Borussia Dortmund v LOSC Lille

Tuesday, March 4 – 9pm CET – Signal Iduna Park

Lille advanced into the knockout stage after finishing seventh on the table, while Dortmund thrashed Sporting Lisbon 3-0 in the playoff round to secure their place. BVB have been solid at home, and online bookmakers have the Bundesliga outfit as -142.86 favourites to defeat their defensibly vulnerable guests.

Borussia Dortmund to win
+196 @ Nags.bet

PSV Eindhoven v Arsenal

Tuesday, March 4 – 9pm CET – Philips Stadion

Arsenal finished third in the league phase, while PSV advanced after their surprise 4-3 aggregate win over Juventus in the playoff round. After slipping out of the Premier League title race, the Gunners should do just enough to extend their four-game win streak against a resilient Dutch side.

Arsenal to win
+107 @ Nags.bet

Real Madrid v Atletico Madrid

Tuesday, March 4 – 9pm CET – Santiago Bernabeu Stadium

Beaten 2-1 by Real Betis on Saturday, reigning champions Real Madrid will have their mettle tested against crosstown rivals Atletico, who were held by Celta Vigo. Expect Carlo Ancelotti’s men to pull out all the stops to avoid a third consecutive stalemate against Atleti, especially with a challenging away fixture looming next week.

Real Madrid to win
+196 @ Nags.bet

Feyenoord v Inter Milan

Wednesday, March 5 – 6:45pm CET – Stadion Feijenoord

Inter finished fourth on the table, while Feyenoord had to go past AC Milan in the playoff round to advance into the last 16. Although Feyenoord has been impressive at home, defeating both Bayern Munich and Milan, the Dutch side may struggle to replicate that success against the in-form Nerazzurri.

Inter Milan to win
-142.86 @ Nags.bet

Bayern Munich v Bayer Leverkusen

Wednesday, March 5 – 9pm CET – Allianz Arena

After advancing into the last 16 following their marginal win over Celtic in the playoff round, Bayern Munich will have their work cut out against Bayer Leverkusen, who secured automatic qualification with a sixth-place finish. While both sides will seek to outdo each other, this high-stakes encounter could end in a stalemate for the third time this season.

Draw
+288 @ Nags.bet

Benfica v Barcelona

Wednesday, March 5 – 9pm CET – Estadio do Sport Lisboa e Benfica

Runners-up Barcelona will fancy their chances against Benfica, who secured their spot in the last 16 following their playoff victory over AS Monaco. Robert Lewandowski scored his 34th goal of the season against Real Sociedad on Sunday, and top soccer betting sites are paying +105 for the Barca forward to add to his tally.

Robert Lewandowski anytime goalscorer
+105 @ Nags.bet

Paris Saint-Germain v Liverpool

Wednesday, March 5 – 9pm CET – Parc des Princes

Top of the Premier League and Champions League standings, Liverpool face a tough test against a PSG side who advanced with a 10-0 aggregate win over Stade Brestois in the playoff round. Since both teams boast impressive attacking might, expect to see plenty of goals in this encounter, with the incomparable Reds ultimately prevailing.

Liverpool to win / Both teams to score
+333 @ Nags.bet