2025 NASCAR Brickyard 400 betting picks & best odds

The NASCAR Cup Series heads to Indianapolis for one of its most historic events — the Brickyard 400. The action starts with practice from 1:05pm EDT on Friday, while the main race is set for 2pm on Sunday.

After returning to the oval layout in 2024, the race quickly reclaimed its Crown Jewel status, complete with the iconic “kissing the bricks” tradition. This 2.5‑mile rectangular oval demands track position and clean air, with 400 miles split into three stages (50-50-60 laps).

This year’s race doubles as the final round of the inaugural In-Season Challenge, with Ty Dillon and Ty Gibbs surprisingly battling for the $1 million bonus. Meanwhile, the field will be fighting for playoff positioning as the regular season winds down.

Denny Hamlin enters as the favorite with the top online sportsbooks after bringing up his fourth win of the season at Dover. Kyle Larson is the defending Brickyard champion, while Chase Elliott and Ryan Blaney remain serious contenders thanks to recent top‑five consistency. Tyler Reddick, who owns the best average finish among active drivers at Indy, offers a strong value play.

NASCAR Brickyard 400 betting odds

• Denny Hamlin – +375
• Kyle Larson – +420
• Ryan Blaney – +540
• Chase Elliott – +825
• Tyler Reddick – +825
• William Byron – +900
• Christopher Bell – +1050
• Chase Briscoe – +1150
• Chris Buescher – +1600
• Brad Keselowski – +2000
• Ty Gibbs – +2800
• Joey Logano – +3300
• Carson Hocevar – +3300
• Bubba Wallace – +4000
• Ross Chastain – +4000
• Alex Bowman – +5000
• Josh Berry – +6600
• Austin Cindric – +6600
• Kyle Busch – +6600
• Ryan Preece – +6600
• John H. Nemechek – +17500
• Daniel Suarez – +17500
• Erik Jones – +17500
• AJ Allmendinger – +30000
• Shane van Gisbergen – +35000
• Cody Ware – +50000
• Katherine Legge – +50000
• Riley Herbst – +50000
• Ty Dillon – +50000
• Josh Bilicki – +50000
• Jesse Love – +50000
• Todd Gilliland – +50000
• Cole Custer – +50000
• Justin Haley – +50000
• Austin Dillon – +50000
• Noah Gragson – +50000
• Michael McDowell – +50000
• Zane Smith – +50000
• Ricky Stenhouse Jr – +50000

More odds available at

NASCAR Brickyard 400 betting predictions

Tyler Reddick to win

Reddick has been ultra-consistent at Indianapolis, averaging a fifth-place finish with two top‑10s in two starts on the oval. He’s shown speed at similar tracks like Pocono and Michigan and remains hungry for his first win of the season. At +825 with , he’s arguably the best value in the field.

Denny Hamlin top‑three finish

Hamlin has finished top five in five of his last seven races, including victories at Dover and Michigan. He dominated stages at Indy last year before wrecking late, and this track remains one of the few major trophies missing from his collection. A podium feels like a smart, low‑risk play at -106.38 odds with .

Chase Briscoe top‑five finish

Briscoe’s momentum is undeniable — four top‑seven finishes in his last six races, including runner‑up last weekend. He won at Pocono earlier this summer and brings that same fast No.19 Toyota back to Indy. On recent form, a top‑five ticket offers solid upside at +150 odds with .