Bundesliga Matchday 4 betting preview & picks | September 19-21

Matchweek 4 of the Bundesliga 2025/26 season brings a stacked slate across Germany, with top-of-the-table Bayern Munich on the road while Borussia Dortmund look to keep pace.

VfB Stuttgart will host St. Pauli to open the Matchweek on Friday, while Dortmund will host Wolfsburg in the final game of the weekend.

Keep reading for our free preview and betting tips for each game, with odds courtesy of the top sportsbooks.

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VfB Stuttgart vs St. Pauli

Friday, September 19 – 8:30pm CEST – MHPArena

Stuttgart’s pressing and wing overloads will stress a St. Pauli defense that concedes space between the lines. St. Pauli can threaten in transitions, but Stuttgart’s sustained territory and chance volume point to a narrow home win.

Werder Bremen vs Freiburg

Saturday, September 20 – 3:30pm CEST – Weserstadion

Expect a slow, physical game with many fouls and set pieces. Freiburg are organized and hard to break down, and Werder Bremen rely on crosses. Both of these squads have scored in each of their three matches.

Augsburg vs Mainz

Saturday, September 20 – 3:30pm CEST – WWK ARENA

Augsburg are direct, strong on set pieces, and usually better at home. Mainz fight, but they struggle to create big chances away from home. In a tight game, the safer call is on the hosts with insurance.

TSG Hoffenheim vs Bayern Munich

Saturday, September 20 – 3:30pm CEST – PreZero Arena

Hoffenheim leave space at the back, and Bayern Munich’s offensive weapons can punish that. Bayern usually create several clear chances and can outscore mistakes. A Bayern win and lots of goals are very likely.

Hamburger SV vs FC Heidenheim

Saturday, September 20 – 3:30pm CEST – Volksparkstadion

Hamburger SV attack with width and crosses often, which suits their home style. FC Heidenheim can counter, but they concede territory on the road. Hamburger’s pressure should tell over the 90 minutes.

RB Leipzig vs FC Koln

Saturday, September 20 – 6:30pm CEST – Red Bull Arena

RB Leipzig press high and attack fast. Köln work hard but struggle to build away from home. If Leipzig score first, they should control the match; however, Koln have shown they can score against anyone.

Eintracht Frankfurt vs Union Berlin

Sunday, September 21 – 3:30pm CEST – Deutsche Bank Park

Eintracht Frankfurt will control the ball and Union Berlin will sit deep and wait for set pieces. Frankfurt will be looking to rebound from their 3-1 loss against Bayer Leverkusen last week, so expect a strong home performance.

Bayer Leverkusen vs Borussia Mönchengladbach

Sunday, September 21 – 5:30pm CEST – BayArena

Bayer Leverkusen move the ball quickly and create cut-backs. Borussia Mönchengladbach can counter, but they leave gaps. Coming off a strong win last week, Leverkusen should make more big chances and pull clear at home.

Borussia Dortmund vs Wolfsburg

Sunday, September 21 – 7:30pm CEST – SIGNAL IDUNA PARK

Borussia Dortmund usually push the pace at home and create through the wings. Wolfsburg can score on breaks, but Dortmund’s pressure should win out. Expect goals at both ends, with the hosts edging it.