EPL Matchweek 1 betting preview & picks | August 15-18, 2025

The 2025/26 English Premier League campaign kicks off on Friday, August 15, when reigning champions Liverpool host Bournemouth at Anfield. Top soccer betting sites have markets open for all 10 games in Matchweek 1, which concludes with Leeds hosting Everton on Monday night.

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Liverpool vs Bournemouth

Friday, August 15 – 8pm BST – Anfield

After claiming the 2024/25 Premier League title in dominant fashion, the Reds added star playmaker Florian Wirtz and young striker Hugo Ekitike to inject youth into their aging squad. Although Liverpool are overwhelming favorites in this clash, expect at least one goal from both sides on opening night.

Aston Villa vs Newcastle United

Saturday, August 16 – 12:30pm BST – Villa Park

Aston Villa will open their season against Newcastle United, who are still dealing with Alexander Isak’s transfer request. Villa have been quiet over the offseason, with little to no player movement. The home side should have the edge in this contest and start the season with a win.

Brighton & Hove Albion vs Fulham

Saturday, August 16 – 3pm BST – American Express Stadium

Brighton and Fulham were two of the most exciting teams to watch throughout the 2024/25 EPL season, with both favoring attacking styles of play. Although the Seagulls lost starting striker Joao Pedro, they should still create plenty of chances — just like their opponents.

Sunderland vs West Ham United

Saturday, August 16 – 3pm BST – Stadium of Light

West Ham open their season against newly promoted Sunderland, with the Irons looking to climb back up the EPL table after finishing 14th in 2024/25. Jarrod Bowen was the Hammers’ main man last season, producing 13 goals and eight assists, and there’s no reason to think that will change this campaign.

Tottenham Hotspur vs Burnley

Saturday, August 16 – 3pm BST – Tottenham Hotspur Stadium

Recently promoted Burnley will travel to London to face Europa League champions Tottenham in Matchweek 1. Thomas Frank takes charge of his first EPL match with Spurs, and if his side can control possession, they should dominate both halves.

Wolverhampton Wanderers vs Manchester City

Saturday, August 16 – 5:30pm BST – Molineux Stadium

Manchester City head into their first EPL season in years without the favorite tag, looking to improve on last year’s third-place finish. Wolverhampton Wanderers have lost key man Matheus Cunha and are expected to struggle. A comfortable City victory looks likely.

Chelsea vs Crystal Palace

Sunday, August 17 – 2pm BST – Stamford Bridge

Chelsea are riding high after their FIFA Club World Cup triumph over the summer and will kick off their campaign against FA Cup winners Crystal Palace. Both teams have scored in each of the last four meetings between these sides, so that market looks appealing for this fixture.

Nottingham Forest vs Brentford

Sunday, August 17 – 2pm BST – The City Ground

Nottingham Forest were the surprise packet of last season, climbing to seventh place with 65 points. Many expect them to hold their position in 2025/26, having kept all their key players. Brentford weren’t as fortunate, losing top scorer Bryan Mbeumo in the offseason. Back the home side.

Manchester United vs Arsenal

Sunday, August 17 – 4:30pm BST – Old Trafford

The highlight of Matchweek 1 will be the clash between Manchester United and Arsenal at Old Trafford. Both sides have added new strikers — the Gunners signing Viktor Gyökeres, and the Red Devils bringing in Benjamin Šeško along with Matheus Cunha and Bryan Mbeumo. Expect attacking football for the full 90 minutes and plenty of goal-scoring opportunities.

Leeds United vs Everton

Monday, August 18 – 8pm CEST – Elland Road

Leeds United will host Everton in their first game back in the top flight, with Elland Road expected to be full for the final day of Matchweek 1. Both teams have strengthened in key positions and look evenly matched across the pitch. Back the unders with top betting sites in what should be a tightly contested match.