NRL Round 21 betting picks, best odds & predictions

Get expert NRL Round 21 betting predictions with game previews, spreads, and multi picks. See who’s winning this week as the finals race heats up.

Sports Betting Tips

by Cayne Pitstock

July 23, 2025 0

The race to the NRL finals heats up this weekend with Round 21 of the 2025 season, featuring several top-eight matchups and some big betting lines. Here are our top rugby league betting tips for every game this round.

Sydney Roosters vs Melbourne Storm

Thursday, July 24 — 7:50pm AEST — Allianz Stadium

Melbourne rarely drop two straight, and with Jahrome Hughes and Harry Grant running the show, they should handle a Roosters squad that’s been inconsistent all season. Xavier Coates’ finishing ability on the edge adds value to any same-game parlay.

Storm -4.5

-111.11 @

North Queensland Cowboys vs St George Illawarra Dragons

Friday, July 25 — 6pm AEST — Queensland Country Bank Stadium

Back home and desperate to stay in the finals hunt, the Cowboys should control this one. Tom Dearden’s game management and Reuben Cotter’s return in the middle give them the edge against a Dragons pack missing key veterans.

Cowboys -4.5

-111.11 @

Brisbane Broncos vs Parramatta Eels

Friday, July 25 — 8pm AEST — Suncorp Stadium

The Broncos are flying with five wins in a row and get Payne Haas and Reece Walsh back in the lineup. Parramatta have been leaking 30 or more points consistently, and even Mitchell Moses’ return won’t patch up their edge defense. Expect Brisbane to cover comfortably at home.

Broncos -13.5

-111.11 @

New Zealand Warriors vs Gold Coast Titans

Saturday, July 26 — 5pm NZST — Go Media Stadium

The Warriors are tough to beat at home, but the Titans usually find a way to keep things scrappy. Expect New Zealand to dominate possession and edge this by a narrow margin, thanks to second-half defensive stops.

Warriors by 1-12

+200 @

Penrith Panthers vs Wests Tigers

Saturday, July 26 — 5:30pm AEST — CommBank Stadium

Nathan Cleary and Isaah Yeo return to bolster the reigning champs, who are back in form. Wests’ attack lacks bite against elite defenses, and Penrith’s home record is outstanding. Look for a double-digit victory.

Panthers -13.5

-111.11 @

South Sydney Rabbitohs vs Cronulla Sharks

Saturday, July 26 — 7:45pm AEST — Polytec Stadium

Cronulla should take the win, but South Sydney’s gritty efforts at home make this close — even though this game is being played in Gosford. Nicho Hynes’ playmaking and Addin Fonua-Blake’s dominance in the middle should be enough for the Sharks to win by a couple of tries.

Sharks by 1-12

+205 @

Canberra Raiders vs Newcastle Knights

Sunday, July 27 — 2pm AEST — GIO Stadium

Top-of-the-table Canberra are ruthless at home and should overpower a struggling Knights side. Their forward pack, led by Joseph Tapine and Josh Papalii, will create the platform for Jamal Fogarty to dictate terms.

Raiders -14.5

-111.11 @

Canterbury Bulldogs vs Manly Sea Eagles

Sunday, July 27 — 4:05pm AEST — Allianz Stadium

Manly’s upset of the Storm showed their ceiling, and with Tom Trbojevic firing at center they’re a real threat. Canterbury rely heavily on defense but lack creativity in attack, leaving openings for Daly Cherry-Evans and Reuben Garrick to cash in late, with the top sports betting sites giving you +145 odds.