Serie A soccer betting tips & top odds | Matchday 5 preview

Serie A Matchday 5 serves up a packed slate across Italy, with early leaders Napoli and Juventus trying to keep momentum while several heavyweights chase form.

From tight mid-table clashes to marquee fixtures, expect contrasting styles and plenty of goalscoring chances.

Keep reading for our free soccer betting tips for Serie A this weekend.

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Como vs US Cremonese

Saturday, September 27 – 3pm CEST – Stadio Giuseppe Sinigaglia

Como are a tough assignment at home, winning twice and sharing the points with Genoa through three home fixtures. Cremonese struggle away, conceding territory and chances from crosses. If Como score first, their game management should mean they find a way to win by at least two goals.

Juventus vs Atalanta

Saturday, September 27 – 6pm CEST – Allianz Stadium

Juventus carry real goal threat with Dušan Vlahović and Jonathan David, especially from crosses and set pieces. Atalanta play on the front foot and leave space in behind, which creates chances at both ends. If either side scores early, this match opens up quickly.

Cagliari vs Inter Milan

Saturday, September 27 – 8:45pm CEST – Unipol Domus

Marcus Thuram is Inter’s main runner between center-backs and attacks low crosses and cutbacks superbly. With service from Federico Dimarco and Denzel Dumfries, he gets multiple close-range chances each game. Cagliari can be exposed on fast transitions and second phases from wide areas. In a match Inter should control, Thuram to score anytime is a straightforward play.

Sassuolo vs Udinese

Sunday, September 28 – 12:30pm CEST – Mapei Stadium

Sassuolo struggle to turn possession into clear chances, while Udinese are compact and hard to break down. Even an early goal is unlikely to open up this game. Expect long spells of midfield play and set pieces with both sides typically cagey.

Pisa vs Fiorentina

Sunday, September 28– 3pm CEST – Arena Garibaldi

Pisa are organized at home and keep games tight, relying on set pieces and counters. Fiorentina create spells of pressure but can struggle to turn territory into clear chances, with just one goal in two away games. Expect a low-margin game where one goal doesn’t break it open.

Roma vs Hellas Verona

Sunday, September 28 – 3pm CEST – Stadio Olimpico

Roma are hard to break down at Stadio Olimpico and typically control territory, limiting shots on target. Hellas Verona struggle to create clear chances away from home and often fade when chasing the game. With Roma’s set-piece threat and compact shape, expect a professional, low-drama win for the hosts.

Lecce vs Bologna

Sunday, September 28 – 6pm CEST – Stadio Ettore Giardiniero

Riccardo Orsolini is Bologna’s main wide threat, drifting inside onto his left and attacking the back post. He has scored three goals in his last five Serie A games and comes up against a Lecce defense which gives up chances from crosses and cutbacks, especially away from home. With Orsolini often involved on penalties and set pieces, back him to score anytime.

AC Milan vs Napoli

Sunday, September 28 – 8:45pm CEST – Stadio Giuseppe Meazza

Both sides love to get on the front foot and pepper the opposition goal. Milan’s wingers create cutbacks and second balls, while Napoli’s forwards thrive on attacking space and set pieces. With defensive lapses on both sides and plenty of match-winners on the pitch, this projects as an open game.

Parma vs Torino

Monday, September 29 – 6:30pm CEST – Stadio Ennio Tardini

Parma are compact and efficient at home, breaking quickly through wide areas and set pieces. Torino’s attack can be blunt on the road, with low shot quality and a tendency to fade when chasing the game. If Parma score first, their structure should prove beneficial.

Genoa vs Lazio

Monday, September 29 – 8:45pm CEST – Stadio Luigi Ferraris

Lazio set up compactly on the road, compressing space and conceding few clear chances. Genoa often labor in slow build-up and struggle when forced to chase. With Lazio’s sharper transitions and set-piece edge, the visitors should fashion the better looks and claim all three points.