US Open women’s final betting picks & odds | Sabalenka v Anisimova

Aryna Sabalenka is one step away from back-to-back women’s singles titles at the US Open, while Amanda Anisimova will be looking slay a demon or two when she takes the court at Arthur Ashe Stadium in New York this Saturday.

Both players did it the hard way in the semifinals. Sabalenka dropped the first set to Jessica Pegula but rallied to win 4-6, 6-3, 6-4, while Anisimova also came from behind in a gripping contest with Naomi Osaka that ended 6-7, 7-6, 6-3 in the American’s favor.

For Sabalenka, this is a golden opportunity to claim a fourth major title and reaffirm her status as the best player on the women’s tennis circuit.

For Anisimova, it is a chance at redemption. She was embarrassed by Iga Swiatek in the Wimbledon final earlier this year, but her win over the Pole in the quarterfinals suggests she has taken all the right lessons from that humbling experience.

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Unsurprisingly, Sabalenka enters the 2025 US Open final as a firm favorite at -208.33 with the top tennis betting sites, while Anisimova is priced at +187 to spring the upset.

Those odds are a smidge tighter than some might have expected, which brings us to an intriguing stat: the underdog holds a distinct head-to-head advantage over the world No.1.

Anisimova has won six of her nine clashes with Sabalenka, including a three-set victory in the Wimbledon semifinals earlier this year when they last met.

There is also the fact Sabalenka has gone 0-2 in major finals this year, which is sure to generate a bit of interest among punters looking for maximum value in the latest US Open betting odds.

Sabalenka v Anisimova US Open 2025 results

Aryna Sabalenka

• SF 4-6, 6-3, 6-4 vs Jessica Pegula
• QF Walkover vs Marketa Vondrousova
• R4 6-1, 6-4 vs Cristina Bucsa
• R3 6-3, 7-6 vs Leylah Fernandez
• R2 7-6, 6-2 vs Polina Kudermetova
• R1 7-5, 6-1 vs Rebeka Masarova

Amanda Anisimova

• SF 6-7, 7-6, 6-3 vs Naomi Osaka
• QF 6-4, 6-3 vs Iga Swiatek
• R4 6-0, 6-3 vs Beatriz Haddad Maia
• R3 6-4, 4-6, 6-2 vs Jaqueline Cristian
• R2 7-6, 6-2 vs Maya Joint
• R1 6-3, 6-2 vs Kimberly Birrell

Best bets for Sabalenka v Anisimova

Match winner – Aryna Sabalenka

When the reigning champion is taking on an up-and-comer playing in only her second major final, you would expect the odds for the favorite to be much shorter. But the head-to-head record and home support for Anisimova mean we are getting a great outright price for Sabalenka. Load up.

To win 2-0 – Aryna Sabalenka

There is obvious appeal in the +120 price for Sabalenka to win in straight sets. The Belarusian is a proven performer on the biggest stage, and after losing two Grand Slam finals in 2025, she will be desperate to convert this time.

To win the first set – Amanda Anisimova

If you want to hedge your bets or steer away from a straight-sets play, there is a bit of value in the +150 price for Anisimova to win the opening set. The 24-year-old has done just that in four of her last six meetings with Sabalenka, who also dropped the opener in her semifinal.