La Liga betting predictions & top picks | Matchday 21

La Liga 2024-25 continues this weekend with a full slate of 10 games lined up between Friday and Monday, including a big matchup between Atletico Madrid and Villarreal. Here are our free soccer betting picks for Matchday 21 of the Spanish Primera Division.

Las Palmas v Osasuna

Friday, January 24 – 9pm CET – Estadio Gran Canaria

Las Palmas, in 14th, have suffered two consecutive defeats, while 10th-placed Osasuna are on a disappointing seven-game winless run. These two sides seem evenly matched and could play out a draw for the third time in four outings.

Real Mallorca v Real Betis

Saturday, January 25 – 2pm CET – Estadi Mallorca Son Moix

Hammered 4-0 by Villarreal last time out, sixth-placed Mallorca will be set on making a quick recovery against Betis, sitting 12th having only managed one win in nine games. Victorious in the reverse fixture, the Bermellones have a great chance of triumphing on home soil.

Atletico Madrid v Villarreal

Saturday, January 25 – 4:15pm CET – Metropolitano Stadium

After slipping to second following their 1-0 defeat to Leganes, Atletico Madrid will be eager to keep their title hopes alive against Villarreal, who are three places below them. Antoine Griezmann has seven league goals thus far, and the Atleti forward remains a solid pick with leading betting sites to add to his tally.

Sevilla v Espanyol

Saturday, January 25 – 6:30pm CET – Ramon Sanchez-Pizjuan Stadium

Sevilla, in 11th, will be looking to ascend higher up the table against struggling Espanyol, who are third from bottom. The hosts, who have dominated this fixture, are firm favourites to secure a fourth consecutive win over the Catalonians.

Real Valladolid v Real Madrid

Saturday, January 25 – 9pm CET – Estadio Jose Zorrilla

Top of La Liga table following last Sunday’s 4-1 win over Palmas, champions Real Madrid will be looking to strengthen their title defence with a win over bottom-placed Valladolid. Rodrygo scored twice during Madrid’s midweek win in the Champions League, and the Brazilian forward is a great pick to strike again with top La Liga betting sites.

Rayo Vallecano v Girona

Sunday, January 26 – 2pm CET – Estadio de Vallecas

Girona are eighth on the table with 28 points, while Vallecano are ninth with two fewer points. The points have been shared in three of their last five meetings, and could do so again.

Real Sociedad v Getafe

Sunday, January 26 – 4:15pm CET – Reale Arena

Real Sociedad, sitting seventh, will continue their push for European football against Getafe, who are in the bottom half of the table. Unbeaten in their last four meetings at the Reale Arena, Sociedad should do just enough to secure a third straight home win in this fixture.

Athletic Bilbao v Leganes

Sunday, January 26 – 6:30pm CET – Estadio de San Mames

Fourth-placed Athletic Bilbao will be seeking to stretch their 11-game unbeaten run against Leganes, who climbed to 15th following their surprise win over Atleti.
Bilbao have form and consistency on their side, and are poised to do the season double on the Pepineros.

Barcelona v Valencia

Sunday, January 26 – 9pm CET – Estadi Olimpic Lluis Companys

Third-placed Barcelona will be looking to end a four-game winless run in La Liga when they host Valencia, who are second from bottom following their 1-0 win over Sociedad. Barca’s Raphinha is in fine form with five goals in his last four games across the board, and online bookmakers are paying +110 for the Brazilian to extend his streak.

Deportivo Alaves v Celta Vigo

Monday, January 27 – 9pm CET – Mendizorrotza Stadium

Celta Vigo slipped to 13th following successive defeats to Vallecano and Bilbao, while Alaves are 17th after one win in eight games. With each side desperate for points, both goalkeepers could be set for a busy night.

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